𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Molecular Dynamics Model of HIV-1 Reverse Transcriptase Complexed with DNA: Comparison with Experimental Structures

✍ Scribed by Leping Li; LeeG. Pedersen; WilliamA. Beard; Katarzyna Bebenek; SamuelH. Wilson; ThomasA. Kunkel; ThomasA. Darden


Publisher
Springer-Verlag
Year
2000
Tongue
English
Weight
360 KB
Volume
6
Category
Article
ISSN
1610-2940

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Molecular Dynamics Simulation of HIV-1 I
✍ Jianping Hu; Cunxin Wang πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 403 KB

The biological function of HIV-1 integrase (IN) is to integrate viral DNA into the host cell chromosome, and the specific binding of IN with viral DNA is a precondition for IN to function correctly. Beforehand, the binding mode of IN dimer (IN 2 ) with the 27 bp segment of viral DNA before 3' proces

Protein–nucleic acid interactions and DN
✍ Jianping Ding; Stephen H. Hughes; Edward Arnold πŸ“‚ Article πŸ“… 1997 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 721 KB

The conformation of the DNA and the interactions of the nucleic acid with the protein in a complex of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) and a 19-mer/18-mer double-stranded DNA template-primer (dsDNA) are described. The structure of this HIV-1 RT complex with dsDN