## Abstract The majority of patients with Angelman syndrome and Prader‐Willi syndrome have a cytogenetic and molecular deletion of chromosome 15q11q13 with the primary difference being in the parental origin of deletion. Our current understanding of the cytogenetics and molecular genetics of these
A molecular and cytogenetic study in Finnish Prader-Willi patients
✍ Scribed by Hannaleena Kokkonen; Marketta Kähkönen; Jaakko Leisti
- Publisher
- Springer
- Year
- 1995
- Tongue
- English
- Weight
- 424 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0340-6717
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W e report on a combined high resolution cytogenetic and fluorescent in situ hybridization study (FISH) on 15 Prader-Willi syndrome (PWS) and 14 Angelman syndrome (AS) patients. High resolution banding showed a microdeletion in the 15qll-q13 region in 7 out of 15 PWS patients, and FISH analysis of t
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