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A Modular, One-Pot, Four-Component Synthesis of Polysubstituted 1,3-Oxazolidines

✍ Scribed by Tejedor, David; Santos-Expósito, Alicia; González-Cruz, David; Marrero-Tellado, José Juan; García-Tellado, Fernando


Book ID
120526961
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
90 KB
Volume
70
Category
Article
ISSN
0022-3263

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## Abstract A tandem one‐pot synthesis of polysubstituted 1,3‐thiazines has been developed by reacting with cyanoacetamide and isothiocyanate derivatives to give rise to 2‐cyano‐3‐mercaptoacrylamides, which are trapped __in situ__ by various aldehydes or diversely substituted ketones through interm