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A modified non-homogeneous model for codon preference and primary sequence structure in protein-coding regions

✍ Scribed by Han Le; Mo Zhong-xi

Publisher
Wuhan University
Year
2002
Tongue
English
Weight
328 KB
Volume
7
Category
Article
ISSN
1007-1202

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The stochastic complexity of a data base of 365 protein-coding regions is analysed. When the primary sequence is modeled as a spatially homogeneous Markov source, the fit to observed codon preference is very poor. The situation improves substantially when a non-homogeneous model is used. Some implic