A modified hepatitis B surface antigen carrying both preS1 and preS2 epitopes
β Scribed by Jingyi Hui; Guangdi Li; Yuying Kong; Yuan Wang
- Book ID
- 105641008
- Publisher
- Science in China Press (SCP)
- Year
- 1998
- Tongue
- English
- Weight
- 788 KB
- Volume
- 41
- Category
- Article
- ISSN
- 1674-7305
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## Abstract The infectious particles of hepatitis B virus (HBV) contain 3 related surface antigens, i.e., small, medium, and large, all of which are encoded by one large open reading frame with multiple initiation codons. The large surface antigen (LβAg) contains preS1, preS2, and S regions while b
The proteins of viral envelope, encoded by the pre-S1 region of HBV-DNA, were measured quantitatively with enzyme immunoassay using monoclonal antibodies directed to pre-S1 epitope and correlated with the expression of pre-S2 region encoded epitope and other HBV markers. In acute HBV infection, both