The model addresses the question of the origin of traveling waves, mimicking waves of the Hh and Dpp proteins, such as found in development of the fly eye. These two proteins, which are part of an important signaling pathway to the genome, are found in a diverse array of developmental situations, fo
A Model of Pattern Formation Based on Signaling Pathways
β Scribed by FREDERICK W. CUMMINGS
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 161 KB
- Volume
- 207
- Category
- Article
- ISSN
- 0022-5193
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β¦ Synopsis
A model of pattern formation in the early embryo is presented. It is motivated by the necessary interaction of kinases and phosphatases, and in particular by the family of Wnt kinase and RPTP phosphatase signaling pathways. It is seen as complementary to the more short-range patterning of the Delta/Notch (or juxtacrine) signaling pathway.
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