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A model of axonal transport drug delivery: effects of diffusivity

โœ Scribed by A.V. Kuznetsov


Book ID
112067343
Publisher
Wiley (John Wiley & Sons)
Year
2012
Tongue
English
Weight
252 KB
Volume
28
Category
Article
ISSN
2040-7939

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Macroscopic modeling of slow axonal tran
โœ A.V. Kuznetsov; A.A. Avramenko; D.G. Blinov ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 312 KB

The purpose of this paper is to develop a macroscopic model of slow axonal transport of soluble proteins which may be transported in axons by both diffusion and active molecular-motor-assisted transport mechanisms. The model relies on the "stop-and-go" hypothesis put forward by Brown et al. [A. Brow