## Abstract The dialysis data of Huang and Ts'o for the cooperative binding of adensine to polyuridylic acid are analyzed here using a grandβpartition function Ising model method similar to that originally employed for polyelectrolytes by Rice and Nagasawa. An appropriate modification permitting th
A model for the binding of adenosine to polyuridylic acid
β Scribed by John G. Burr; Terence L. McDowell; Sherril D. Christian
- Book ID
- 119405550
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- English
- Weight
- 279 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0006-291X
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π SIMILAR VOLUMES
The binding of adenosine-14C to polyuridylic acid (poly (U)) and several modified poly-(U)s has been studied by equilibrium dialysis. The poly(U) was modified by addition of appropriate reagents across the 5,6-double bond of the uracil ring to form the photohydrate, photodimer, dihydrouracil, the HO
Spectrophotometric measurements were made on the extent of binding of formaldehyde to polyuridylic acid under conditions of varying temperature and formaldehyde concentration. The data is interpreted in terms of a temperature-dependent stacking of the bases in poly U at 20Β°, but not at 40Β°C. A theor