𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A mitochondrial frameshift suppressor maps in the tRNASer-var1region of the mitochondrial genome of the yeastS. cerevisiae

✍ Scribed by Brigitte Weiss-Brummer; Hajime Sakai; Alexander Hüttenhofer

Publisher
Springer-Verlag
Year
1989
Tongue
English
Weight
729 KB
Volume
15
Category
Article
ISSN
0172-8083

No coin nor oath required. For personal study only.

✦ Synopsis

A polypeptide chain-terminating mutation (M5631) previously has been shown to be a +1T insertion in the yeast mitochondrial gene oxi1, coding for subunit II of the cytochrome c oxidase. A spontaneously arisen frameshift suppressor (mfs-1) that is mitochondrially inherited suppresses this mutation to a considerable extent. The suppressor mutation was mapped by genetic and molecular analyses in the mitochondrial tRNASer-var1 region of the mitochondrial genome of the yeast S. cerevisiae. Genetic analyses show that the suppressor mfs-1 does not suppress other known mitochondrial frameshift mutations, or missense and nonsense mutations.

📜 SIMILAR VOLUMES

A mitochondrial frameshift-suppressor (+
A mitochondrial frameshift-suppressor (+) of the yeastS. cerevisiaemaps in the mitochondrial 15S rRNA locus
✍ Brigitte Weiss-Brummer; Hajime Sakai; Fritz Kaudewitz 📂 Article 📅 1987 🏛 Springer-Verlag 🌐 English ⚖ 707 KB

The first case of a +1 "extrageneic" frameshift suppressor (MF1), mapping in the yeast mitochondrial 15S rRNA gene is reported. The suppressor was identified by genetic analyses in a leaky mitochondrial oxil frameshift mutant and the respective wild-type strain 777-3A of the yeast S. cerevisiae. Thi

Physical map of the COB region in mitoch
Physical map of the COB region in mitochondrial DNA ofSaccharomyces cerevisiae
✍ G. Grosch; C. Schmelzer; S. Mathews 📂 Article 📅 1981 🏛 Springer-Verlag 🌐 English ⚖ 539 KB

A physical map of the COB region in mtDNA of yeast has been established. This region harbours a split gene coding for apocytochrome b. It includes restriction sites of seven endonucleases (EcoRI, HindII, HindIII, HaeIII, HpaII, AluI and BamHI). Various mtDNA sequences of this region, retained in a s