A Mild, Nonbasic Synthesis of Thioethers. The Copper-Catalyzed Coupling of Boronic Acids with N-Thio(alkyl, aryl, heteroaryl)imides.

A Mild and Efficient Method for N-Arylnu

A Mild and Efficient Method for N-Arylnucleobase Synthesis via the Cross-Coupling Reactions of Nucleobases with Arylboronic Acids Catalyzed by Simple Copper Salts

✍ Lan Tao; Yang Yue; Ji Zhang; Shan-Yong Chen; Xiao-Qi Yu 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 German ⚖ 176 KB

## Abstract A simple and efficient copper‐salt catalyzed __N__‐arylation of nucleobases is reported. In a mixed solvent of MeOH and H~2~O, the coupling products were obtained in moderate to excellent yields at room temperature within a short time. A variety of substituted __N__‐aryl nucleobases can