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A mild mutator phenotype arises in a mouse model for malignancies associated with neurofibromatosis type 1

โœ Scribed by Rene Garza; Robert A. Hudson III; C. Alex McMahan; Christi A. Walter; Kristine S. Vogel


Book ID
113808978
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
334 KB
Volume
615
Category
Article
ISSN
0027-5107

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## Communicated by Arthur L. Beaudet We have developed a rapid screening method to detect a recurrent mutation in the neurofibromatosis type 1 gene. Using gene amplification and hybridization with allele-specific oligonucleotides, we screened 97 unrelated affected individuals for the recurrent C+T