A Mild Method for the Preparation of γ-Hydroxy-α,β-Acetylenic Esters
✍ Scribed by Shatrughan P. Shahi; Kazunori Koide
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 108 KB
- Volume
- 116
- Category
- Article
- ISSN
- 0044-8249
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📜 SIMILAR VOLUMES
The formation of 4-alkoxy-2(5H)-furan-A C H T U N G T R E N N U N G ones was achieved via tandem alkoxylation/lactonization of g-hydroxy-a,b-acetylenic esters catalyzed by 2 mol% of [2,6-bis(diisopropylphenyl)imidazol-2-ylidine]gold bis(trifluoromethanesulfonyl)imidate
g-Hydroxy-a,b-acetylenic esters containing three adjacent and structurally very different functional groups are very useful in the synthesis of highly functionalized organic molecules. [1, 2] This class of compound is normally prepared by treatment of an alkyl propiolate with nBuLi at À78 8C