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A mild and selective method for cleavage of O-acetyl groups with dibutyltin oxide

โœ Scribed by Hong-Min Liu; Xuebin Yan; Wen Li; Conghai Huang


Book ID
108309403
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
134 KB
Volume
337
Category
Article
ISSN
0008-6215

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A mild and selective method for the clea
โœ Randy W Jackson ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 89 KB

A method for the cleavage of t-butyl esters using silica gel in refluxing toluene is reported. Good yields of the corresponding carboxylic acids are obtained, and the reaction is selective for t-butyl esters over t-butyl ethers and trimethylsilylethyl (TMSE) esters.