A mild and efficient method for the reduction of oximes to imines for futher in situ reactions
β Scribed by Barton, Derek H. R.; Motherwell, William B.; Simon, Ethan S.; Zard, Samir Z.
- Book ID
- 121283449
- Publisher
- The Royal Society of Chemistry
- Year
- 1984
- Tongue
- English
- Weight
- 154 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0022-4936
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
A new and mild method for reducing 2' amides to carbinolamine ethers and imines and its use in the synthesis of pyrrolo [l,4]btnzodiazepine antibiotics is reported.
Chlorotrimethylsilane -sodium iodide reagent (in situ generation of iodotrimethylsilane)in acetonitrile reduces alkyl and aryl/aroyl azides to the corresponding amines/amides in excellent yields under neutral and mild conditions.