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A mild and efficient method for aromatic chlorination of electron-rich arylalkyl amines

✍ Scribed by Guixue Yu; Helen J Mason; Ximao Wu; Masaki Endo; James Douglas; John E Macor

Publisher: Elsevier Science
Year: 2001
Tongue: French
Weight: 68 KB
Volume: 42
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)00430-0

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✦ Synopsis

Sulfuryl chloride was used to chlorinate electron-rich arylalkyl amines in a mild and efficient one-pot transformation with simple product isolation via precipitation. Protection of the amines was not needed.

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