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A micelle-shedding thermosensitive hydrogel as sustained release formulation

✍ Scribed by de Graaf, Albert J.; Azevedo Próspero dos Santos, Inês I.; Pieters, Ebel H.E.; Rijkers, Dirk T.S.; van Nostrum, Cornelus F.; Vermonden, Tina; Kok, Robbert J.; Hennink, Wim E.; Mastrobattista, Enrico

Book ID
119291803
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
1014 KB
Volume
162
Category
Article
ISSN
0168-3659

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## Abstract In this work, a biodegradable poly(ethylene glycol)‐poly(ε‐caprolactone)‐poly (ethylene glycol) (PEG‐PCL‐PEG, PECE) triblock copolymer was successfully synthesized, which was flowing sol at low temperature and turned to nonflowing gel at body temperature. The toxicity evaluation of PECE