PIeton oan be oubalkoqlated in tha &omitlon br re-
A method for the benzoannulation of ketones
✍ Scribed by Leo A. Paquette; William P. Melega; James D. Ḱramer
- Publisher
- Elsevier Science
- Year
- 1976
- Tongue
- French
- Weight
- 234 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0040-4039
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We have recently reported' a method for the synthesis of u-substituted a,f? -unsaturated carbonyl compounds in which an oxalyl ketone or ester (1) is condensed with an aldehyde, JIJ generating a diketo lactone (z). Mild base cleavage then completes the synthesis.
Tha,Uium ethotide in chLo?~o6olun wa6 6ound Xo bL a pa&icLLeahey vdu.ab.k combivation doh the 4eahrrangtment 06 B-hy&oxyb&nides to ke..tona. We recently found 1 that a-selenoalkyllithiums bearing two alkyl groups on the carbanionic center are valuable reagents for the ring enlargement of cyclic ket
A bmp& &JO b&p @ocedtie wkLch &owb thehug en&mgement 05 cg&c h&ones .U d&c&abed wtuch ties advan.tage 06 the kcgh nucf.coph.&utg 04 a-beiiWw~kg~-.~O%IMM towahdb ctibongL compoundd and 06 a nov& Rhwpou.-kon ma&on wkcch OCCWLA on tithe hebting 6-hgdkoxgbelencdea.