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A method for monitoring the effectiveness of allopurinol pretreatment in the prevention of ischemic/reperfusion injury

✍ Scribed by D.V. Godin; K.M. Ko; A.K. Qayumi; W.R.E. Jamieson

Book ID
116097091
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
661 KB
Volume
22
Category
Article
ISSN
0160-5402

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The therapeutic benefits of allopurinol pretreatment in renal ischaemia-reperfusion injury were investigated by monitoring renal malondialdehyde (MDA) and ATP levels together with calculated MDA/ATP ratio in ischaemic (45 min) and reperfused (15 min) rat kidneys. MDA levels remained unchanged during