𝔖 Bobbio Scriptorium
✦   LIBER   ✦

A Method for Estimating Penetrance from Families Sampled for Linkage Analysis

✍ Scribed by Yuanjia Wang; Ruth Ottman; Daniel Rabinowitz

Book ID
109223552
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
294 KB
Volume
62
Category
Article
ISSN
0006-341X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

A nonparametric method for penetrance fu
A nonparametric method for penetrance function estimation
✍ F. Alarcon; C. BonaΓ―ti-PelliΓ©; H. Harari-Kermadec πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 173 KB

## Abstract In diseases caused by a deleterious gene mutation, knowledge of age‐specific cumulative risks is necessary for medical management of mutation carriers. When pedigrees are ascertained through at least one affected individual, ascertainment bias can be corrected by using a parametric meth

A haplotype-linkage analysis method for
A haplotype-linkage analysis method for estimating recombination rates using dense SNP trio data
✍ Lue Ping Zhao; Shuying Sue Li; Fumin Shen πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 543 KB

## Abstract Meiotic recombination is an important evolution force in shaping human genomes and creating human diversity. Recent explorations suggest that meiotic recombination events tend to happen in certain regions of the genome, leading to the hypothesis of recombination hot spots. To identify s