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A metastatic colon cancer model using nonoperative transanal rectal injection

โœ Scribed by Melissa Donigan; Bryan D. Loh; Laurie S. Norcross; Shuan Li; Paul R. Williamson; Samuel DeJesus; Andrea Ferrara; Joseph T. Gallagher; Cheryl H. Baker


Book ID
106155807
Publisher
Springer
Year
2009
Tongue
English
Weight
282 KB
Volume
24
Category
Article
ISSN
0930-2794

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We have developed a liver metastatic model of human colon cancer using severe combined immunodeficient (SCID) mice. Liver metastases were observed in all the SCID mice on day 28 after intrasplenic injection with 5 X lo6 dissociated tumor cells of COL-2-JCK, a human colon cancer strain serially trans