Examination of a reaction intermediate i
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Ya-Jun Zheng; Douglas B. Jordan; Der-Ing Liao
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Article
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2003
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Elsevier Science
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English
⚖ 251 KB
The riboflavin synthase catalyzed reaction proceeds through a pentacyclic intermediate of undetermined stereochemistry. Calculations at the B3LYP/6-31G(d) level of theory indicate that the trans pentacyclic structure is favored over the cis by 3.3kcal/mol. A model of the the trans, but not the cis,