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A melanin-dispersing effect of cyclic adenosine monophosphate on Fundulus melanophores

✍ Scribed by R. R. Novales; R. Fujii

Publisher
John Wiley and Sons
Year
1970
Tongue
English
Weight
213 KB
Volume
75
Category
Article
ISSN
0021-9541

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✦ Synopsis

Abstract

Treatment of Fundulus melanophores with adenosine 3′,5′‐monophosphate (cyclic AMP) is followed by reversible melanin dispersion in these cells. Adenosine 3′‐monophosphate and adenosine 5′‐monophosphate both have a similar, but weaker dispersing action. In addition, adenosine 5′‐monophosphate also has a melanin aggregating effect. These results are interpreted to mean that nerve transmitters may act by controlling the level of cyclic AMP within the Fundulus melanophore.

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