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A mechanistic study on the amination of 2-chloro-3,5-dinitropyridine with liquid ammonia

โœ Scribed by De Bie, Dick A.; Geurtsen, Bart; Berg, Iekje E.; Van der Plas, Henk C.


Book ID
111910500
Publisher
American Chemical Society
Year
1986
Tongue
English
Weight
456 KB
Volume
51
Category
Article
ISSN
0022-3263

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Nucleophilic substitution at the pyridin
โœ Ezzat A. Hamed ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 129 KB ๐Ÿ‘ 2 views

The reaction rates of 2-chloro-3,5-dinitropyridine 1 with a series of arylthiolates 2a-h in methanol have been measured at 25ยฐC. The products are the corresponding 2-thioaryl-3,5-dinitropyridine 3a-h. Good Hammett correlation with value ฯช1.19 was obtained suggesting an elimination-addition mechanism