✦ LIBER ✦

A Mathematical Model of the Effect of Immunogenicity on Therapeutic Protein Pharmacokinetics

✍ Scribed by Chen, Xiaoying; Hickling, Timothy; Kraynov, Eugenia; Kuang, Bing; Parng, Chuenlei; Vicini, Paolo

Book ID: 125405811
Publisher: American Association of Pharmaceutical Scientists
Year: 2013
Tongue: English
Weight: 964 KB
Volume: 15
Category: Article
ISSN: 1550-7416
DOI: 10.1208/s12248-013-9517-z

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

The Utility of Modeling and Simulation A

The Utility of Modeling and Simulation Approaches to Evaluate Immunogenicity Effect on the Therapeutic Protein Pharmacokinetics

✍ Juan Jose Perez Ruixo, Peiming Ma, Andrew T. Chow 📂 Article 📅 2012 🏛 American Association of Pharmaceutical Scientists 🌐 English ⚖ 643 KB

Immunogenicity of Therapeutic Proteins:

Immunogenicity of Therapeutic Proteins: The Use of Animal Models

✍ Vera Brinks; Wim Jiskoot; Huub Schellekens 📂 Article 📅 2011 🏛 Springer US 🌐 English ⚖ 156 KB

Reflections on the immunogenicity of the

Reflections on the immunogenicity of therapeutic proteins

✍ G. Antonelli 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 39 KB

Modeling Effects of Protein Binding on F

Modeling Effects of Protein Binding on Fosphenytoin Pharmacokinetics

✍ Olson, S.C.; Kugler, A.R. 📂 Article 📅 1996 🏛 Nature Publishing Group 🌐 English ⚖ 111 KB

Glass particles as an adjuvant: A model

Glass particles as an adjuvant: A model for adverse immunogenicity of therapeutic proteins

✍ Amber Haynes Fradkin; John F. Carpenter; Theodore W. Randolph 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 334 KB

Unwanted immune responses to parenterally administered therapeutic proteins pose serious safety and economic risks, but the mechanism(s) by which these responses are generated are unknown. We measured immune responses to aggregates of recombinant murine growth hormone (mGH) formed by agitation or fr

Utility of population pharmacokinetic mo

Utility of population pharmacokinetic modeling in the assessment of therapeutic protein-drug interactions

✍ Chow, Andrew T.; Earp, Justin C.; Gupta, Manish; Hanley, William; Hu, Chuanpu; W 📂 Article 📅 2013 🏛 Sage Publications 🌐 English ⚖ 238 KB