This paper considers the comparison of experimental spatial and temporal data of mitotic rates measured during corneal epithelial wound healing (CEWH) of a rat model with the predictions of a computer modelling framework. We begin by briefly showing that previous models, used in the study of corneal
A mathematical model of intercellular signaling during epithelial wound healing
β Scribed by Filippo Posta; Tom Chou
- Book ID
- 108196617
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 454 KB
- Volume
- 266
- Category
- Article
- ISSN
- 0022-5193
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The stimuli for the increase in epidermal mitosis during wound healing are not fully known. We construct a mathematical model which suggests that biochemical regulation of mitosis is fundamental to the process, and that a single chemical with a simple regulatory effect can account for the healing of
## Abstract Mechanisms that specifically modulate cell spreading and/or cell migration following epithelial wounding are poorly understood. Using microβwounded human gastric epithelial monolayers, we show herein that EGF and TGFΞ± maximally increase spreading of epithelial sheets under a cell prolif
## Abstract The coordinated migration of keratinocytes is crucial to cutaneous wound healing; failure of keratinocytes to migrate into a wound can lead to chronic nonβhealing wounds. Keratinocyte migration can be influenced by applied electrical fields. Our aim was to investigate whether keratinocy