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A mathematical model of caspase function in apoptosis

✍ Scribed by Varner, Jeffrey; Fussenegger, Martin; Bailey, James E.


Book ID
109828602
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
478 KB
Volume
18
Category
Article
ISSN
1087-0156

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## Abstract A number of pro‐apoptotic stimuli induce the activation of caspase‐9, an initiator protease that activates executioner caspases, such as caspase‐3, leading to the development of programmed cell death. Here we demonstrate that cell (platelets and pancreatic acinar cells) stimulation with