## Abstract ฮฒโamyloid peptide (Aฮฒ) has been implicated in the pathogenesis of Alzheimer disease and has been reported to induce apoptotic death in cell culture. Cysteine proteases, a family of enzymes known as caspases, mediate cell death in many models of apoptosis. Multiple caspases have been imp
Role of caspases in neuronal apoptosis
โ Scribed by Roseann Ventimiglia; Lit-Fui Lau; Ross A. Kinloch; Andrew Hopkins; Eric H. Karran; Lawrence P. Petalidis; Robin V. Ward
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 213 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0272-4391
- DOI
- 10.1002/ddr.1155
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In Alzheimer's disease (AD) synapses degenerate and neurons die in brain regions involved in learning and memory processes. Although the cellular and molecular mechanisms underlying the neurodegenerative process in AD are unclear, increasing evidence suggests roles for amyloid โค-peptide (Aโค) and bio