A macromolecular inhibitor of glutamine synthetase activity in tomato root extracts
✍ Scribed by Fernando Gallardo; Francisco M. Cánovas
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 592 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0031-9422
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Immature and mature rat astroglia in culture were assayed for glutamine synthetase (GS) activity after a single exposure to the epileptogen FeCI2. Cells were cultured with both standard and elevated extracellular potassium or glutamate (Glu) concentrations. FeCI2 reduced GS activity below control le
The present study investigated the anticonvulsant profile of Withania somnifera (W.s) in a lithium-pilocarpine model of status epilepticus (SE) in rats. Acute treatment with the root extract of W.s prolonged the latency to forelimb clonus but failed to protect against mortality. Acute pretreatment w