A human melanoma metastasis-suppressor l
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Mary E. Miele; Matthew D. Jewett; Steven F. Goldberg; David L. Hyatt; Christina
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Article
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2000
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John Wiley and Sons
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French
⚖ 105 KB
Loss, deletion or rearrangement along large portions of the long arm (q-arm) of chromosome 6 occurs in >80% of late-stage human melanomas, suggesting that genes controlling malignant characteristics are encoded there. Metastasis, but not tumorigenicity, was completely suppressed in the human melanom