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A Liquid Chromatographic Electrochemical Assay for S-2-(3-Aminopropylamino) Ethylphosphorothioate (WR2721) in Human Plasma

โœ Scribed by Shaw, L. M.; Bonner, H.; Turrisi, A.; Norfleet, A. L.; Glover, D. J.


Book ID
125845617
Publisher
Informa UK (Taylor & Francis)
Year
1984
Tongue
English
Weight
668 KB
Volume
7
Category
Article
ISSN
0148-3919

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## Polyethylene glycol-modified urate oxidase (PEG-uricase) holds promise as a hypouricemic agent for treating gout and as an adjunct to cytolytic therapy of hematologic malignancies. Spectrophotometric assays of urate oxidase are not sensitive enough for pharmacokinetic evaluation of PEG-uricase