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High-Performance Liquid Chromatographic Assay of Zonisamide (1,2-benzisoxazole-3-methanesulfonamide) in Human Plasma using a Solid-Phase Extraction Technique

✍ Scribed by K.H. Liu; Y.K. Lee; Y.E. Sunwoo; K.S. Yu; W. Kang; S.S. Lee; Y.R. Yoon; J.G. Shin


Book ID
111788003
Publisher
Springer
Year
2004
Tongue
English
Weight
202 KB
Volume
59
Category
Article
ISSN
0009-5893

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An HPLC method for the determination of phenylephrine and its conjugates in human plasma was developed and validated. The method for quantitation involved extraction of diluted plasma (subject to hydrolysis with beta-glucuronidase for 30 min with 500 units of enzyme per 0.1 ml of plasma at 37 degree