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A kinetic study of the oxidation effects of amphotericin B on human low-density lipoproteins

✍ Scribed by Joanna Barwicz; Ilona Gruda; Pierre Tancrède

Book ID
117111952
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
135 KB
Volume
465
Category
Article
ISSN
0014-5793

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Amphotericin B toxicity as related to the formation of oxidatively modified low-density lipoproteins
✍ Joanna Barwicz; Isabelle Dumont; Claire Ouellet; Ilona Gruda 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 518 KB

The effect of amphotericin B on the oxidation and degradation of low- and high-density lipoproteins was investigated by UV-vis spectroscopy, electron microscopy, electrophoresis, and size-exclusion chromatography. Two formulations of the drug were used: the commercial Fungizone and a new, less toxic