A kinetic study of erythrocyte-DNA/anti-DNA immune complex association and dissociation reactions in systemic lupus erythematosus
β Scribed by Meryhew, Nancy L.; Westling, Paul R.; Erdmans, Marjorie E.; Janecek, Elizabeth J.; Runquist, Olaf A.
- Book ID
- 121775416
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 595 KB
- Volume
- 991
- Category
- Article
- ISSN
- 0304-4165
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
To examine autoantibodies present in patients with active systemic lupus erythematosus (SLE), sera, circulating immune comptexes (CIC), and antibodies purified on DNA-immunoadsorbent were tested by enzyme immunoassay. A panel of self-antigens, including DNA, histones (HIS), glomerular basal membrane
We examined the effect of DNase treatment of sera with antihistone activity. In non-systemic lupus erythematosus (SLE) sera, antihistone levels remained unmodified, but a significant decrease was observed in 7 of 11 SLE sera with anti-DNA antibodies. This was accompanied in some by an increase in an