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The prognostic and therapeutic implications of DNA:Anti-DNA immune complexes in systemic lupus erythematosus (SLE)

✍ Scribed by Emil J.Bardana Jr.; Ronald J. Harbeck; Andree A. Hoffman; Bernard Pirofsky; Ronald I. Carr


Book ID
115676371
Publisher
Elsevier Science
Year
1975
Tongue
English
Weight
951 KB
Volume
59
Category
Article
ISSN
1555-7162

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DNA–ANTI-DNA Complexes account for part
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We examined the effect of DNase treatment of sera with antihistone activity. In non-systemic lupus erythematosus (SLE) sera, antihistone levels remained unmodified, but a significant decrease was observed in 7 of 11 SLE sera with anti-DNA antibodies. This was accompanied in some by an increase in an