The low penicillin-producing, single gene copy strain Wis54-1255 was used to study the effect of overexpressing the penicillin biosynthetic genes in Penicillium chrysogenum. Transformants of Wis54-1255 were obtained with the amdS expression-cassette using the four combinations: pcbAB, pcbC, pcbC-pen
A kinetic model for the penicillin biosynthetic pathway in Penicillium chrysogenum
✍ Scribed by J. Nielsen; H.S. Jørgensen
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 544 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0967-0661
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract As is often the case for microbial product formation, the penicillin production rate of __Penicillium chrysogenum__ has been observed to be a function of the growth rate of the organism. The relation between the biomass specific rate of penicillin formation (__q__~p~) and growth rate (_
## Abstract Important steps in metabolic pathways are formed by the transport of substrates and products over the cell membrane. The study of in vivo transport kinetics requires accurate quantification of intra‐ and extracellular levels of the transported compounds. Especially in case of extracellu