A kinetic and thermodynamic study of the lipase-catalyzed remote resolution of a chiral tertiary alcohol
β Scribed by Shi-Zhen Wang; Jian-Ping Wu; Gang Xu; Li-Rong Yang
- Book ID
- 113489905
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 421 KB
- Volume
- 65
- Category
- Article
- ISSN
- 1369-703X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
As part of our investigation of structure-activity relationships in a Candida rugosa lipase-catalyzed ester hydrolysis reaction, methyl 2-(octylsulfinyl)benzoate has been studied, with respect to rate and enantioselectivity behaviour, using two different lipase preparations. A chiral normal-phase li
## Abstract Lipaseβcatalyzed kinetic resolution of racemates is a popular method for synthesis of chiral synthons. Most of these resolutions are reversible equilibrium limited reactions. For the first time, an extensive kinetic model is proposed for kinetic resolution reactions, which takes into ac