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A kinetic and thermodynamic study of the lipase-catalyzed remote resolution of a chiral tertiary alcohol

✍ Scribed by Shi-Zhen Wang; Jian-Ping Wu; Gang Xu; Li-Rong Yang


Book ID
113489905
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
421 KB
Volume
65
Category
Article
ISSN
1369-703X

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## Abstract Lipase‐catalyzed kinetic resolution of racemates is a popular method for synthesis of chiral synthons. Most of these resolutions are reversible equilibrium limited reactions. For the first time, an extensive kinetic model is proposed for kinetic resolution reactions, which takes into ac