Stereocontrolled route to a key intermed
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E.J. Corey; Mark G. Bock
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Article
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1975
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Elsevier Science
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French
โ 210 KB
We have undertaken a synthesis of this substance as part of a broader program in the area of biologically active macrocyclic natural products. One attractive approach to the synthesis of maytansine involves the introduction of chiraltty at carbons 3, 4, 5, 10, and 9 after formation of the macro ring