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A hydroxymethyl sulphate ester as an active metabolite of the carcinogen, 5-hydroxymethylchrysene

✍ Scribed by Haruhiro Okuda; Akira Hiratsuka; Hiroshi Nojima; Tadashi Watabe

Book ID: 115778887
Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 646 KB
Volume: 35
Category: Article
ISSN: 0006-2952
DOI: 10.1016/0006-2952(86)90232-7

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## Abstract 7,12‐Dimethylbenz(a)anthracene and three of its metabolites were tested for carcinogenic activity by in vitro incubation with murine pulmonary tissue for 2 days followed by implantation of the explants into isologous mice. 7‐Hydroxymethyl‐12‐methylbenz(a) anthracene and 12‐hydroxymethyl