A hybrid clustering of protein binding sites
✍ Scribed by Gábor Iván; Zoltán Szabadka; Vince Grolmusz
- Book ID
- 111313442
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 637 KB
- Volume
- 277
- Category
- Article
- ISSN
- 1432-1327
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## Abstract The gas‐phase chemistry of anionic [M + Cat^2+^ – 3H]^−^ complexes between Ca^2+^‐specific peptides and the alkaline earth metal ions Mg^2+^, Ca^2+^ and Ba^2+^ is reported. The metal ion complexes were studied using fast atom bombardment, collision‐induced decomposition (CID) and molecu
We have developed a strategy for grafting a protein-protein interface based on the known crystal structure of a native ligand and receptor proteins in a complex. The key interaction residues at the ligand protein binding interface are transferred onto a scaffold protein so that the mutated scaffold