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A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers

✍ Scribed by Bischoff, J. R.

Book ID: 111745442
Publisher: Nature Publishing Group
Year: 1998
Tongue: English
Weight: 857 KB
Volume: 17
Category: Article
ISSN: 0261-4189
DOI: 10.1093/emboj/17.11.3052

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## Abstract Aurora‐A kinase is considered a potential cancer susceptibility gene that encodes a centrosome‐associated, cell cycle‐regulated serine/threonine kinase. We studied two single nucleotide polymorphisms (SNP) in the coding region of Aurora‐A, 91T‐to‐A (F31I) and 169G‐to‐A (V57I). We studie