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A highly stereoselective synthesis of indolyl N-substituted glycines

✍ Scribed by Biao Jiang; Cai-Guang Yang; Xiao-Hui Gu


Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
139 KB
Volume
42
Category
Article
ISSN
0040-4039

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✦ Synopsis


Optically active a-indolyl N-substituted glycines were synthesized by reaction of an indolyl boronic acid with glyoxylic acid using chiral methylbenzylamine as the chiral auxiliary with high diastereoselectivity. The absolute configuration of the product was determined by a single-crystal X-ray analysis.


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ChemInform Abstract: Stereoselective Syn
✍ Tushar K. Chakraborty; Sanjib Das; T. Venugopal Raju πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 30 KB πŸ‘ 1 views

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