A highly stereocontrolled synthetic approach to 1,6-dideoxy-6,6-difluoroazasugar derivatives
β Scribed by Tomoya Kitazume; Kouichi Murata; Akiko Okabe; Youichiro Takahashi; Takashi Yamazaki
- Book ID
- 103976982
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 850 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0957-4166
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A synthesis of a functionalized bicyclo[6.2.1]undecane, N- (7-hydroxymethyl-bicyclo[6.2.1]undeca-3,5,9-trien-2-yl)-4methyl-benzenesulfonamide, is described. Starting with a [6+4] cycloaddition between cyclopentadiene and cycloheptatrienone, the final product was prepared in five steps with an overal
## Abstract For Abstract see ChemInform Abstract in Full Text.
+)-7-Deoxy-6-epicastanospermine 1, (-)-7,8-dideoxy-6-epicastanospermine 2 and (-)-Nacetylslaframine 4 have been synthesized via the stereoselective intramolecular iodocyclization of trichloroacetimidates generated from cis-olefinic allylic alcohols 7 and 15, respectively.