✍ Scribed by Wei Wang; Fanzuo Kong
No coin nor oath required. For personal study only.
Linked acetylated di-, tri-, and telrasaccharides were synthesized in satisfactory yields and good stereoselectivities by a new method--orthoester formation and rearrangement under mild conditions.
📜 SIMILAR VOLUMES
Sterically congested glycosides, glycosyl-13-(1--->4)-glycosides, were stereoselectively synthesized by reduction of glycosidic spiro-orthoesters with LiAIH4-AICI3. This novel transformation is especially valuable when it is applied to the preparation of mannosyl-13-(1--->4)-glycoside which must be
A Highly Stereoselective β-(1→4)-Glycosidic Bond Formation by Reductive Cleavage of Cyclic Orthoesters. -Reduction of the orthoester (I) under the conditions shown provides the desired glycoside (II) with high β-selectivity. Application of a LiAlH4/AlCl3 reagent to the glycosidic spiro-orthoesters
l-+6)-P-D-Galactopyranan was synthesized by cationic ring-opening polymerization of 1,6-anhydro-2-O-benzoyl-3,4-di-O-henzyl-P-D-galactopyranose and subsequent deprotection. The polymerization proceeded at 0" and 20", using 10-50 mol% of phosphorus pentafluoride as initiator in dichloromethane, to g