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A highly efficient synthesis of (Z) γ-iodo allylic alcohols

✍ Scribed by Ilane Marek; Alexandre Alexakis; Jean-F. Normant


Book ID
108381938
Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
203 KB
Volume
32
Category
Article
ISSN
0040-4039

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A stereoselective synthesis of β,γ-disub
✍ Mitsuhisa Tamura; Gohu Suzukamo 📂 Article 📅 1981 🏛 Elsevier Science 🌐 French ⚖ 190 KB

Reaction of alkyllithiums 1 with isoprene epoxide 2 gives B,y-disubstituted allylic alcohols 2 of Z-configuration. The reaction of \*-lithiotricyclene as alkyllithium gives o-santalol 5, which is one of the main constituents in East Indian sandalwood oil.