A Highly Efficient Synthesis of (−)-PI-091 Construction of the 4-Alkoxy-2-butene-4-lactam Skeleton from Fischer-Type Carbene Complexes, Alkynyllithiums, and Tosyl Isocyanate

ChemInform Abstract: A Highly Efficient

ChemInform Abstract: A Highly Efficient Synthesis of (-)-PI-091 Construction of the 4- Alkoxy-2-butene-4-lactam Skeleton from Fischer-Type Carbene Complexes, Alkynyllithiums, and Tosyl Isocyanate.

✍ N. IWASAWA; K. MAEYAMA 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 35 KB 👁 2 views

A Highly Efficient Synthesis of (-)-PI-091 Construction of the 4-Alkoxy-2-butene-4-lactam Skeleton from Fischer-Type Carbene Complexes, Alkynyllithiums, and Tosyl Isocyanate. -A general and facile method for the construction of lactams such as ( IV) is developed by the reaction of the propargyl met