A highly efficient method for solvent-free synthesis of bisarylmethylidenes of pyranones and thiopyranones

✍ Scribed by M. Saeed Abaee; Mohammad M. Mojtahedi; M. Mehdi Zahedi; Roholah Sharifi

• Publisher: John Wiley and Sons
• Year: 2007
• Tongue: English
• Weight: 152 KB
• Volume: 18
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.20252

✦ Synopsis

A remarkable efficient double crossed aldol condensation of heterocyclic ketones with a variety of aromatic aldehydes is described at room temperature in the presence of magnesium bromide ethyl etherate, triethylamine, and methanol under solvent-free conditions. Excellent yields of 3,5-bisarylmethylidenes of pyranones and thiopyranones are achieved in a facile one-pot general procedure.