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A highly efficient method for solvent-free synthesis of bis(arylmethylidene)piperidinones

✍ Scribed by M. Saeed Abaee; Mohammad M. Mojtahedi; Roholah Sharifi; M. MehdiZahedi

Publisher
Journal of Heterocyclic Chemistry
Year
2007
Tongue
English
Weight
184 KB
Volume
44
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

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A remarkably efficient double crossed aldol condensation of piperidin‐4‐one with various aromatic aldehydes is described at room temperature in the presence of diethylamine and lithium perchlorate under solvent‐free conditions. Excellent yields of 3,5‐bis(arylmethylidene)piperidinones are achieved in a facile one‐pot general procedure. Structure of the products is determined by spectroscopic methods and elemental analysis.

πŸ“œ SIMILAR VOLUMES

A highly efficient method for solvent-fr
A highly efficient method for solvent-free synthesis of bisarylmethylidenes of pyranones and thiopyranones
✍ M. Saeed Abaee; Mohammad M. Mojtahedi; M. Mehdi Zahedi; Roholah Sharifi πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 152 KB

A remarkable efficient double crossed aldol condensation of heterocyclic ketones with a variety of aromatic aldehydes is described at room temperature in the presence of magnesium bromide ethyl etherate, triethylamine, and methanol under solvent-free conditions. Excellent yields of 3,5-bisarylmethyl