A heterochromatic homogeneously staining region (HSR) in the karyotype of a human breast carcinoma cell line
β Scribed by P.E. Barker; Y.-F. Lau; T.C. Hsu
- Book ID
- 119102465
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- English
- Weight
- 842 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0165-4608
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## Abstract A modified comparative genomic hybridization (mCGH) technique was applied to a series of 17 primary breast carcinomas in which cytogenetic study (CG) demonstrated the presence of homogeneously staining region(s), suggesting the occurrence of DNA amplification. mCGH demonstrated recurren
## Abstract The cell line CIPL38 was derived from the pleural effusion of a patient with small cell lung cancer. The karyotype was hyperdiploid and complex with a variable number of marker chromosomes. Two of the markers had large homogeneously staining regions (hsr), which were shown to consist of