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A herpes simplex virus type 1 ICP22 deletion mutant is altered for virulence and latency in vivo

✍ Scribed by K. L. Poffenberger; A. D. Idowu; E. B. Fraser-Smith; P. E. Raichlen; R. C. Herman


Book ID
105151293
Publisher
Springer Vienna
Year
1994
Tongue
English
Weight
852 KB
Volume
139
Category
Article
ISSN
1432-8798

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Preliminary characterization of a mutant
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In this paper we report on the preliminary characterization of a mutant of herpes simplex virus type. 1 (HSV-1) selected for acycloguanosine (acyclovir, ACV) resistance in vitro. The ACV' virus was examined for a series of parameters that include chemosensitivity assay, thymidine kinase (TK) activit