✦ LIBER ✦

A Guide to Drug Discovery: Target selection in drug discovery

✍ Scribed by Knowles, Jonathan; Gromo, Gianni

Book ID: 109951592
Publisher: Nature Publishing Group
Year: 2003
Tongue: English
Weight: 358 KB
Volume: 2
Category: Article
ISSN: 1474-1776
DOI: 10.1038/nrd986

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

In-SilicoApproaches to Multi-target Drug

In-SilicoApproaches to Multi-target Drug Discovery

✍ Xiao Hua Ma; Zhe Shi; Chunyan Tan; Yuyang Jiang; Mei Lin Go; Boon Chuan Low; Yu 📂 Article 📅 2010 🏛 Springer US 🌐 English ⚖ 559 KB

A guide to drug discovery: Combinatorial

A guide to drug discovery: Combinatorial compound libraries for drug discovery: an ongoing challenge

✍ Mario Geysen, H.; Schoenen, Frank; Wagner, David; Wagner, Richard 📂 Article 📅 2003 🏛 Nature Publishing Group 🌐 English ⚖ 628 KB

Target deconvolution strategies in drug

Target deconvolution strategies in drug discovery

✍ Schlüpen, Christina; Raggiaschi, Roberto; Gaviraghi, Giovanni; Terstappen, Georg 📂 Article 📅 2007 🏛 Nature Publishing Group 🌐 English ⚖ 995 KB

A guide to drug discovery: Predicting th

A guide to drug discovery: Predicting therapeutic value in the lead optimization phase of drug discovery

✍ Kenakin, Terry 📂 Article 📅 2003 🏛 Nature Publishing Group 🌐 English ⚖ 932 KB

A guide to drug discovery: The role of t

A guide to drug discovery: The role of the medicinal chemist in drug discovery — then and now

✍ Lombardino, Joseph G.; Lowe, John A. 📂 Article 📅 2004 🏛 Nature Publishing Group 🌐 English ⚖ 245 KB

HIV integrase: a target for drug discove

HIV integrase: a target for drug discovery

✍ Ramon Puras Lutzke; Ronald Plasterk 📂 Article 📅 1997 🏛 Blackwell Publishing 🌐 English ⚖ 536 KB

Current antiviral strategies against HIV rely on structure–function analysis of HIV reverse transcriptase (RT) and protease (PR). The third viral __pol__ gene product, HIV integrase (IN), is also a good target for drug discovery, since IN is essential for retroviral replication and, moreover, it has